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For transduction, 200 l lentiviral supernatant was thawed on ice and added to HCC-1806 cells together with 8 mg ml 1 Polybrene (hexadimethrine bromide

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Spermidine was able to inhibit HAT activity in aging yeast, inhibit oxidative stress and necrosis, and trigger deacetylation of histone H3 (Eisenberg et al., 2009)