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By now, it has been established that the primary function of GLP-1 and GLP-1RA is to modulate brain regions that regulate appetite by influencing the release of neurotransmitters and peptides involved in hunger and energy balance
People taking them often feel full sooner, eat less, and their bodies metabolize food more effectively
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Some patients find that remaining on a lower maintenance dose of Ozempic (such as 0.5 mg weekly rather than progressing to 1 mg or 2 mg) provides adequate glycaemic control whilst minimising gastrointestinal adverse effects
Moreover, several studies showed no differences in insulin or IR in obese PWS patients and controls [3, 4]
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