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In the presence of redox-active ions (iron, copper), vitamin C acts as a prooxidant, contributing to the formation of hydroxyl radicals, that may lead to lipid, DNA, or protein oxidation [810]
Symptoms of Oxidative Stress: While internal, it manifests as premature aging of all body systems, including skin, brain, and organs
IP3 may trigger the release of calcium ions (Ca2+) from intracellular stores, while DAG may activate protein kinase C (PKC)
What to Know About Knee Gel Injections (Viscosupplementation). HSS Health Library, 2024
Finally, oxidative stress can lead to synovial hyperplasia science-speak for too many cells growing in the joints and cause bone and cartilage damage
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