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Because PT-141 acts centrally rather than via the vasculature, some providers may use it alongside other treatments when appropriate

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226,227 It appears to have complex effects on brain chemistry, with some studies suggesting it increases levels of GABA, modulates dopamine and serotonin levels, affects the function of NMDA glutamate receptors involved in nerve excitement, and increases levels of brain-derived neurotrophic factor, a protein that stimulates nerve growth and inter-neuron connections

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BPC-157 is a 15-amino acid peptide (sequence: GEPPPGKPADDAGLV) that is native and stable in human gastric juice