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Pre-treatment evaluation by your doctor is essential to rule out contraindications, such as hypersensitivity. Note to readers: This article is for informational purposes only and not a substitute for professional medical advice

Most apolipoproteins are associated with HDL which serves as the reservoir and which function, in part, to facilitate transfer of some apolipoproteins to VLDL and chylomicrons

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However, there is a limitation to the utility of LXR agonists as shown by the first generation synthetic LXR ligands which activate both LXRs and lead to marked increases in hepatic lipogenesis and plasma triglyceride levels