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If the liver is depleted of glutathione, it cannot efficiently clear the surging histamine levels
Retrieved 11 January 2023
Yet metabolite effects are compartment- and dose-dependent: acetate can fuel tumor-intrinsic c-Mycdependent PD-L1 upregulation and immune evasion in other solid tumors, underscoring the need for cell-selective or receptor-selective delivery [82]
Week 3+ : Increase to 300-500 mcg if needed 4
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