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Differences between GLP-1R agonists GLP-1R agonists already in the market and others in development present the same mode of action and, having the same pleiotropic effects of native GLP-1, the differences in clinical profiles between them are related to differences in pharmacokinetics, structure and size of each formulation

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Gastroparesis patients retain over 60% at two hours or over 10% at four hours, creating conditions where food ferments, forms solid bezoar masses, and prevents nutrition absorption

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